Dr. Mario 64

Dr. Mario 64 is a puzzle game for Nintendo 64 that captures the charm of the original Dr. Mario series in full 3D. If you grew up matching colored pills to viruses or simply enjoy relaxing puzzle gameplay, this cartridge offers hundreds of hours of entertainment.

Dr. Mario 64 Gameplay and Features

• Classic puzzle-matching mechanics translated to the N64 with new visual perspective
• Multiple game modes for solo and multiplayer fun
• Colorful, engaging gameplay that appeals to both casual and dedicated players
• Physical Nintendo 64 cartridge for authentic retro gaming

Condition: Pre-Owned. This is a puzzle game released in the early 2000s that remains a favorite among N64 collectors and puzzle fans. The Nintendo 64 library holds dozens of memorable titles across every genre, and Dr. Mario 64 stands out as a title worth revisiting or discovering for the first time.

Buying pre-owned means you get genuine retro gaming at a fraction of the cost of sealed copies, with the added benefit of knowing the game plays as expected. Whether you prefer to pick up your copy in-store at Most Wanted or have it shipped to you, we’re here to make it easy. Browse more Nintendo 64 games to complete your collection.