Dr. Mario

Dr. Mario GameBoy is a puzzle game where you guide Mario as he works to eliminate viruses by dropping two-colored medical capsules into a medicine bottle. The playfield fills with red, yellow, and blue viruses that you must match and clear using strategy and quick reflexes.

Dr. Mario GameBoy Highlights

• Classic falling-block puzzle gameplay with side-view perspective
• Head-to-head multiplayer for up to 2 players on Game Boy
• Developed by Nintendo and released in 1990
• Addictive tile-matching action that rewards both planning and speed

This is a puzzle and strategy game that appeals to anyone who enjoys brain-teasing gameplay. The Game Boy version brings that satisfying, portable puzzle experience to Nintendo’s handheld system, making it perfect for quick sessions or extended play. Condition: Pre-Owned. The combination of simple rules and escalating challenge has made this title a favorite among retro game collectors and puzzle fans for over three decades.

Buying pre-owned is a smart way to enjoy classic games affordably while supporting the second-hand market. We test and stand behind every title we sell, and you can pick it up in person at Most Wanted locations or have it shipped directly to you. Browse more Game Boy games and build your handheld collection today.